Search on: 3',5'-CYCLIC-AMP PHOSPHODIESTERASES 
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Descriptor English:   3',5'-Cyclic-AMP Phosphodiesterases 
Descriptor Spanish:   3',5'-AMP Cíclico Fosfodiesterasas 
Descriptor Portuguese:   3',5'-AMP Cíclico Fosfodiesterases 
Synonyms English:   CAMP Phosphodiesterase
3',5'-Cyclic AMP 5'-Nucleotidohydrolase
3',5'-Cyclic-Nucleotide Phosphodiesterase  
Tree Number:   D08.811.277.352.640.150
D12.644.360.008
D12.776.476.008
Definition English:   Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are widely distributed in animal tissue and control the level of intracellular cyclic AMP. Many specific enzymes classified under this heading demonstrate additional spcificity for 3',5'-cyclic IMP and CYCLIC GMP. 
Indexing Annotation English:   general; prefer specifics; DF: 3 5 CYCL NPD
History Note English:   1994 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   31725 
Unique Identifier:   D015105 

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